Varaico: Literature-Extracted Genetic Variants

Gene:STK3
Variant:p.R451W

STK3

108 papers

RefSeq Summary

This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase remo...

Pfam Domains

Pkinaseaa 27–278UCSCProtein kinase domain
Mst1_SARAHaa 437–484UCSCC terminal SARAH domain of Mst1

Gene Aliases

HGNC Name

serine/threonine kinase 3

HGNC Alias Symbols

MST2; KRS1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_006281.4
p.R451W
c.1351C>T
Surrounding Variants
1 paper
NM_006281.4
p.R451Q
c.1352G>A
1 paper
NM_006281.4
p.E447Q
c.1339G>C
1 paper
NM_006281.4
p.D456Y
c.1366G>T
2 papers
NM_006281.4
p.N442fs
c.1324_1325fs
1 paper
NM_006281.4
p.E460K
c.1378G>A
1 paper
NM_006281.4
p.R461Q
c.1382G>A
1 paper
NM_006281.4
p.F439_L440Splc
c.1318-4C>G
1 paper
NM_006281.4
p.E465K
c.1393G>A
1 paper
NM_006281.4
p.Q468H
c.1404G>T
1 paper
NM_006281.4
p.Q468H
c.1404G>C
1 paper
NM_006281.4
p.Y470C
c.1409A>G
1 paper
NM_006281.4
p.T471A
c.1411A>G
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