Varaico: Literature-Extracted Genetic Variants

Gene:STK3
Variant:p.R178fs

STK3

108 papers

RefSeq Summary

This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase remo...

Pfam Domains

Pkinaseaa 27–278UCSCProtein kinase domain
Mst1_SARAHaa 437–484UCSCC terminal SARAH domain of Mst1

Gene Aliases

HGNC Name

serine/threonine kinase 3

HGNC Alias Symbols

MST2; KRS1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_006281.4
p.R178fs
c.532_533fs
Surrounding Variants
3 papers
NM_006281.4
p.R178H
c.533G>A
1 paper
NM_006281.4
p.R178C
c.532C>T
1 paper
NM_006281.4
p.N179S
c.536A>G
1 paper
NM_006281.4
p.T180A
c.538A>G
1 paper
NM_006281.4
p.T180I
c.539C>T
1 paper
NM_006281.4
p.V181L
c.541G>T
1 paper
NM_006281.4
p.V181L
c.541G>C
1 paper
NM_006281.4
p.A176S
c.526G>T
1 paper
NM_006281.4
p.D173V
c.518A>T
1 paper
NM_006281.4
p.T184A
c.550A>G
1 paper
NM_006281.4
p.D173Y
c.517G>T
1 paper
NM_006281.4
p.M188T
c.563T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."