Varaico: Literature-Extracted Genetic Variants

Gene:STK3
Variant:p.H144Y

STK3

108 papers

RefSeq Summary

This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase remo...

Pfam Domains

Pkinaseaa 27–278UCSCProtein kinase domain
Mst1_SARAHaa 437–484UCSCC terminal SARAH domain of Mst1

Gene Aliases

HGNC Name

serine/threonine kinase 3

HGNC Alias Symbols

MST2; KRS1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_006281.4
p.H144Y
c.430C>T
Surrounding Variants
1 paper
NM_006281.4
p.R145T
c.434G>C
1 paper
NM_006281.4
p.R145K
c.434G>A
1 paper
NM_006281.4
p.K142R
c.425A>G
1 paper
NM_006281.4
p.D146Y
c.436G>T
6 papers
NM_006281.4
p.D146N
c.436G>A
1 paper
NM_006281.4
p.R141I
c.422G>T
1 paper
NM_006281.4
p.H138Y
c.412C>T
2 papers
NM_006281.4
p.G150V
c.449G>T
1 paper
NM_006281.4
p.L153F
c.457C>T
1 paper
NM_006281.4
p.G133*
c.397G>T
1 paper
NM_006281.4
p.K132N
c.396A>T
1 paper
NM_006281.4
p.K132N
c.396A>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."