syntaxin binding protein 5

tomosyn

LLGL3

tomosyn-1

Syntaxin-binding protein 5

Lethal(2) giant larvae protein homolog 3

Tomosyn-1

Lethal giant larvae(Lgl) like, C-terminal

Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

Varaico: Literature-Extracted Genetic Variants

STXBP5

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols