Varaico: Literature-Extracted Genetic Variants

Gene:SUCLA2
Variant:p.F345L

SUCLA2

188 papers

RefSeq Summary

Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by th...

Pfam Domains

ATP-grasp_2aa 54–262UCSCATP-grasp domain
Ligase_CoAaa 321–441UCSCCoA-ligase

Gene Aliases

HGNC Name

succinate-CoA ligase ADP-forming subunit beta

HGNC Previous Symbol

LINC00444

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003850.3
p.F345L
c.1035C>G
Surrounding Variants
1 paper
NM_003850.3
p.F345L
c.1035C>A
1 paper
NM_003850.3
p.F345L
c.1033T>C
1 paper
NM_003850.3
p.N344S
c.1031A>G
1 paper
NM_003850.3
p.V348G
c.1043T>G
7 papers
NM_003850.3
p.G350S
c.1048G>A
6 papers
NM_003850.3
p.G350V
c.1049G>T
1 paper
NM_003850.3
p.V357V
c.1071A>G
11 papers
NM_003850.3
p.D333G
c.998A>G
2 papers
NM_003850.3
p.D333Y
c.997G>T
1 paper
NM_003850.3
p.D333H
c.997G>C
1 paper
NM_003850.3
p.A360T
c.1078G>A
1 paper
NM_003850.3
p.T331A
c.991A>G
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