Varaico: Literature-Extracted Genetic Variants

Gene:SUCLA2
Variant:p.S185_H187Fs

SUCLA2

188 papers

RefSeq Summary

Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by th...

Pfam Domains

ATP-grasp_2aa 54–262UCSCATP-grasp domain
Ligase_CoAaa 321–441UCSCCoA-ligase

Gene Aliases

HGNC Name

succinate-CoA ligase ADP-forming subunit beta

HGNC Previous Symbol

LINC00444

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003850.3
p.S185_H187Fs
c.554_559delinsTGTGFs
Surrounding Variants
1 paper
NM_003850.3
p.G188D
c.563G>A
1 paper
NM_003850.3
p.G189S
c.565G>A
1 paper
NM_003850.3
p.G189delFs
c.566delC
1 paper
NM_003850.3
p.G189insFs
c.567dupT
3 papers
NM_003850.3
p.G184R
c.550G>A
2 papers
NM_003850.3
p.V190G
c.569T>G
1 paper
NM_003850.3
p.N191insFs
c.572_573ins4
1 paper
NM_003850.3
p.V181Fs
c.543delinsTAFs
1 paper
NM_003850.3
p.D194N
c.580G>A
7 papers
NM_003850.3
p.S199T
c.595T>A
1 paper
NM_003850.3
p.I203T
c.608T>C
1 paper
NM_003850.3
p.P207L
c.620C>T
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