Varaico: Literature-Extracted Genetic Variants

SUCLG1

154 papers

RefSeq Summary

This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to ...

Pfam Domains

CoA_bindingaa 53–146UCSCCoA binding domain

Ligase_CoAaa 199–324UCSCCoA-ligase

Gene Aliases

HGNC Name

succinate-CoA ligase GDP/ADP-forming subunit alpha

HGNC Previous Names

succinate-CoA ligase, GDP-forming, alpha subunit; succinate-CoA ligase, alpha subunit

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003849.4

p.N171H

c.511A>C

Surrounding Variants

5 papers

NM_003849.4

p.N171S

c.512A>G

1 paper

NM_003849.4

p.P170L

c.509C>T

8 papers

NM_003849.4

p.P170R

c.509C>G

1 paper

NM_003849.4

p.C172R

c.514T>C

1 paper

NM_003849.4

p.C172Y

c.515G>A

1 paper

NM_003849.4

p.G169E

c.506G>A

1 paper

NM_003849.4

p.P173T

c.517C>A

1 paper

NM_003849.4

p.P173R

c.518C>G

1 paper

NM_003849.4

p.I176N

c.527T>A

1 paper

NM_003849.4

p.N177_P178Splc

c.531+1G>A

3 papers

NM_003849.4

p.N177_P178Splc

c.531+4A>T

1 paper

NM_003849.4

p.R161H

c.482G>A