small ubiquitin like modifier 1

UBL1

PIC1

GMP1

SMT3C

SUMO-1

SMT3H3

OFC10

ubiquitin-like 1 (sentrin)

SMT3 suppressor of mif two 3 homolog 1 (yeast)

SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)

Small ubiquitin-related modifier 1

GAP-modifying protein 1

SMT3 homolog 3

Sentrin

Ubiquitin-homology domain protein PIC1

Ubiquitin-like protein SMT3C

Ubiquitin-like protein UBL1

Smt3C

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008].

Varaico: Literature-Extracted Genetic Variants

SUMO1

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol