Varaico: Literature-Extracted Genetic Variants

SUPT16H

151 papers

RefSeq Summary

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged i...

Pfam Domains

FACT-Spt16_Nlobaa 5–167UCSCFACT complex subunit SPT16 N-terminal lobe domain

Peptidase_M24aa 181–411UCSCMetallopeptidase family M24

SPT16aa 529–651UCSCFACT complex subunit (SPT16/CDC68)

PH_SPT16aa 660–787UCSCFACT complex subunit SPT16 PH-like domain

Rttp106-like_middleaa 807–895UCSCHistone chaperone Rttp106-like, middle domain

SPT16_Caa 927–1020UCSCFACT complex subunit SPT16, C-terminal domain

Gene Aliases

HGNC Name

SPT16 homolog, facilitates chromatin remodeling subunit

HGNC Alias Symbols

FACT; FACTP140; SPT16/CDC68; FLJ14010; FLJ10857; CDC68

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007192.4

p.K725R

c.2174A>G

Surrounding Variants

1 paper

NM_007192.4

p.G714R

c.2140G>C

1 paper

NM_007192.4

p.G714R

c.2140G>A

1 paper

NM_007192.4

p.K696fs

c.2086_2087fs

3 papers

NM_007192.4

p.R693Q

c.2078G>A

1 paper

NM_007192.4

p.R693*

c.2077C>T

1 paper

NM_007192.4

p.N685S

c.2054A>G

1 paper

NM_007192.4

p.L680P

c.2039T>C

1 paper

NM_007192.4

p.K674R

c.2021A>G

1 paper

NM_007192.4

p.R657W

c.1969C>T

1 paper

NM_007192.4

p.D649Y

c.1945G>T

2 papers

NM_007192.4

p.Q648R

c.1943A>G

1 paper

NM_007192.4

p.G731W

c.2191G>T