Varaico: Literature-Extracted Genetic Variants

SUPT16H

151 papers

RefSeq Summary

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged i...

Pfam Domains

FACT-Spt16_Nlobaa 5–167UCSCFACT complex subunit SPT16 N-terminal lobe domain

Peptidase_M24aa 181–411UCSCMetallopeptidase family M24

SPT16aa 529–651UCSCFACT complex subunit (SPT16/CDC68)

PH_SPT16aa 660–787UCSCFACT complex subunit SPT16 PH-like domain

Rttp106-like_middleaa 807–895UCSCHistone chaperone Rttp106-like, middle domain

SPT16_Caa 927–1020UCSCFACT complex subunit SPT16, C-terminal domain

Gene Aliases

HGNC Name

SPT16 homolog, facilitates chromatin remodeling subunit

HGNC Alias Symbols

FACT; FACTP140; SPT16/CDC68; FLJ14010; FLJ10857; CDC68

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007192.4

p.N585Y

c.1753A>T

Surrounding Variants

1 paper

NM_007192.4

p.N582_E583Fs

c.1746_1747delinsCFs

1 paper

NM_007192.4

p.A592T

c.1774G>A

1 paper

NM_007192.4

p.N571K

c.1713C>G

1 paper

NM_007192.4

p.N571K

c.1713C>A

3 papers

NM_007192.4

p.N571S

c.1712A>G

1 paper

NM_007192.4

p.R569G

c.1705C>G

1 paper

NM_007192.4

p.S560S

c.1680C>T

2 papers

NM_007192.4

p.S558N

c.1673G>A

1 paper

NM_007192.4

p.E536K

c.1606G>A

1 paper

NM_007192.4

p.K534E

c.1600A>G

1 paper

NM_007192.4

p.K528E

c.1582A>G

1 paper

NM_007192.4

p.R525W

c.1573C>T