Varaico: Literature-Extracted Genetic Variants

SUPT16H

151 papers

RefSeq Summary

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged i...

Pfam Domains

FACT-Spt16_Nlobaa 5–167UCSCFACT complex subunit SPT16 N-terminal lobe domain

Peptidase_M24aa 181–411UCSCMetallopeptidase family M24

SPT16aa 529–651UCSCFACT complex subunit (SPT16/CDC68)

PH_SPT16aa 660–787UCSCFACT complex subunit SPT16 PH-like domain

Rttp106-like_middleaa 807–895UCSCHistone chaperone Rttp106-like, middle domain

SPT16_Caa 927–1020UCSCFACT complex subunit SPT16, C-terminal domain

Gene Aliases

HGNC Name

SPT16 homolog, facilitates chromatin remodeling subunit

HGNC Alias Symbols

FACT; FACTP140; SPT16/CDC68; FLJ14010; FLJ10857; CDC68

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_007192.4

p.L61R

c.182T>G

Surrounding Variants

1 paper

NM_007192.4

p.L61P

c.182T>C

1 paper

NM_007192.4

p.L61V

c.181C>G

1 paper

NM_007192.4

p.L61I

c.181C>A

1 paper

NM_007192.4

p.G58G

c.174T>A

1 paper

NM_007192.4

p.G58D

c.173G>A

1 paper

NM_007192.4

p.T64I

c.191C>T

1 paper

NM_007192.4

p.K79E

c.235A>G

1 paper

NM_007192.4

p.K80_V82delFs

c.239_245del7

1 paper

NM_007192.4

p.F84L

c.250T>C

1 paper

NM_007192.4

p.F84L

c.252C>G

1 paper

NM_007192.4

p.F84L

c.252C>A

1 paper

NM_007192.4

p.G93S

c.277G>A