Varaico: Literature-Extracted Genetic Variants

SUPT16H

151 papers

RefSeq Summary

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged i...

Pfam Domains

FACT-Spt16_Nlobaa 5–167UCSCFACT complex subunit SPT16 N-terminal lobe domain

Peptidase_M24aa 181–411UCSCMetallopeptidase family M24

SPT16aa 529–651UCSCFACT complex subunit (SPT16/CDC68)

PH_SPT16aa 660–787UCSCFACT complex subunit SPT16 PH-like domain

Rttp106-like_middleaa 807–895UCSCHistone chaperone Rttp106-like, middle domain

SPT16_Caa 927–1020UCSCFACT complex subunit SPT16, C-terminal domain

Gene Aliases

HGNC Name

SPT16 homolog, facilitates chromatin remodeling subunit

HGNC Alias Symbols

FACT; FACTP140; SPT16/CDC68; FLJ14010; FLJ10857; CDC68

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007192.4

p.K23R

c.68A>G

Surrounding Variants

1 paper

NM_007192.4

p.K23Q

c.67A>C

1 paper

NM_007192.4

p.D26G

c.77A>G

1 paper

NM_007192.4

p.A33insFs

c.99dupC

1 paper

NM_007192.4

p.V36E

c.107T>A

1 paper

NM_007192.4

p.V40D

c.119T>A

1 paper

NM_007192.4

p.D41_E42del1

c.123_125delTCA

2 papers

NM_007192.4

p.K48R

c.143A>G

1 paper

NM_007192.4

p.T50I

c.149C>T

1 paper

NM_007192.4

p.Q53insFs

c.157_158insA

1 paper

NM_007192.4

p.G58D

c.173G>A

1 paper

NM_007192.4

p.G58G

c.174T>A

1 paper

NM_007192.4

p.L61V

c.181C>G