Varaico: Literature-Extracted Genetic Variants

Gene:TAB2
Variant:p.T291_P295del5

TAB2

191 papers

RefSeq Summary

The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with ...

Pfam Domains

CUEaa 9–50UCSCCUE domain

Gene Aliases

HGNC Name

TGF-beta activated kinase 1 (MAP3K7) binding protein 2

HGNC Previous Symbol

MAP3K7IP2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001292034.3
p.T291_P295del5
c.871_884del15
Surrounding Variants
1 paper
NM_001292034.3
p.T292A
c.874A>G
1 paper
NM_001292034.3
p.S289insFs
c.866dupC
1 paper
NM_001292034.3
p.S293delFs
c.878delC
3 papers
NM_001292034.3
p.S293*
c.878C>A
3 papers
NM_001292034.3
p.S293*
c.878C>G
1 paper
NM_001292034.3
p.P286L
c.857C>T
1 paper
NM_001292034.3
p.P295_P296delFs
c.885_886delAC
1 paper
NM_001292034.3
p.P286delFs
c.857delC
1 paper
NM_001292034.3
p.P296fs
c.886_887fs
1 paper
NM_001292034.3
p.P296L
c.887C>T
1 paper
NM_001292034.3
p.S300*
c.899C>A
1 paper
NM_001292034.3
p.S300*
c.899C>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."