Varaico: Literature-Extracted Genetic Variants

Gene:TAB2
Variant:p.P374insFs

TAB2

191 papers

RefSeq Summary

The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with ...

Pfam Domains

CUEaa 9–50UCSCCUE domain

Gene Aliases

HGNC Name

TGF-beta activated kinase 1 (MAP3K7) binding protein 2

HGNC Previous Symbol

MAP3K7IP2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001292034.3
p.P374insFs
c.1121dupC
Surrounding Variants
1 paper
NM_001292034.3
p.N375fs
c.1123_1124fs
1 paper
NM_001292034.3
p.N375fs
c.1123_1124fs
1 paper
NM_001292034.3
p.T376M
c.1127C>T
1 paper
NM_001292034.3
p.P365P
c.1095C>T
1 paper
NM_001292034.3
p.Y388_I389delFs
c.1164_1165delTA
1 paper
NM_001292034.3
p.S390delFs
c.1168delT
1 paper
NM_001292034.3
p.S390fs
c.1168_1169fs
1 paper
NM_001292034.3
p.S354*
c.1061C>A
1 paper
NM_001292034.3
p.S354*
c.1061C>G
1 paper
NM_001292034.3
p.A391G
c.1172C>G
1 paper
NM_001292034.3
p.S352delFs
c.1056delC
1 paper
NM_001292034.3
p.T351I
c.1052C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."