Varaico: Literature-Extracted Genetic Variants

TACC3

199 papers

RefSeq Summary

This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This prot...

Pfam Domains

Aurora-A_bind_TACC3aa 522–563UCSCTACC3, Aurora-A binding region

TACC_Caa 639–832UCSCTransforming acidic coiled-coil-containing protein (TACC), C-terminal

Gene Aliases

HGNC Name

transforming acidic coiled-coil containing protein 3

HGNC Alias Symbols

ERIC1; ERIC-1; maskin; Tacc4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006342.3

p.Q4Q

c.12G>A

Surrounding Variants

3 papers

NM_006342.3

p.Q4H

c.12G>C

1 paper

NM_006342.3

p.Q4R

c.11A>G

1 paper

NM_006342.3

p.V5I

c.13G>A

1 paper

NM_006342.3

p.D8fs

c.22_23fs

1 paper

NM_006342.3

p.K9insFs

c.25dupA

1 paper

NM_006342.3

p.V11_S12delins

c.33_34delinsCT

1 paper

NM_006342.3

p.N13delins

c.38_39delinsTT

1 paper

NM_006342.3

p.E14insFs

c.41dupA

1 paper

NM_006342.3

p.E14fs

c.40_41fs

1 paper

NM_006342.3

p.N16K

c.48T>A

1 paper

NM_006342.3

p.F24Y

c.71T>A

1 paper

NM_006342.3

p.F24L

c.72T>A