Varaico: Literature-Extracted Genetic Variants

TACC3

199 papers

RefSeq Summary

This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This prot...

Pfam Domains

Aurora-A_bind_TACC3aa 522–563UCSCTACC3, Aurora-A binding region

TACC_Caa 639–832UCSCTransforming acidic coiled-coil-containing protein (TACC), C-terminal

Gene Aliases

HGNC Name

transforming acidic coiled-coil containing protein 3

HGNC Alias Symbols

ERIC1; ERIC-1; maskin; Tacc4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006342.3

p.Q104delFs

c.311delA

Surrounding Variants

1 paper

NM_006342.3

p.I106I

c.318C>T

1 paper

NM_006342.3

p.P121S

c.361C>T

1 paper

NM_006342.3

p.E123K

c.367G>A

1 paper

NM_006342.3

p.E123G

c.368A>G

2 papers

NM_006342.3

p.A124P

c.370G>C

1 paper

NM_006342.3

p.G130fs

c.388_389fs

1 paper

NM_006342.3

p.D131Y

c.391G>T

1 paper

NM_006342.3

p.G139S

c.415G>A

3 papers

NM_006342.3

p.E143K

c.427G>A

1 paper

NM_006342.3

p.G145R

c.433G>C

1 paper

NM_006342.3

p.A148T

c.442G>A

1 paper

NM_006342.3

p.S156G

c.466A>G