Varaico: Literature-Extracted Genetic Variants

TACC3

199 papers

RefSeq Summary

This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This prot...

Pfam Domains

Aurora-A_bind_TACC3aa 522–563UCSCTACC3, Aurora-A binding region

TACC_Caa 639–832UCSCTransforming acidic coiled-coil-containing protein (TACC), C-terminal

Gene Aliases

HGNC Name

transforming acidic coiled-coil containing protein 3

HGNC Alias Symbols

ERIC1; ERIC-1; maskin; Tacc4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_006342.3

p.P395R

c.1184C>G

Surrounding Variants

1 paper

NM_006342.3

p.E392D

c.1176G>C

1 paper

NM_006342.3

p.E392D

c.1176G>T

1 paper

NM_006342.3

p.S399A

c.1195T>G

1 paper

NM_006342.3

p.A390A

c.1170A>G

1 paper

NM_006342.3

p.R400Q

c.1199G>A

1 paper

NM_006342.3

p.G386D

c.1157G>A

1 paper

NM_006342.3

p.V381E

c.1142T>A

1 paper

NM_006342.3

p.D412G

c.1235A>G

1 paper

NM_006342.3

p.P413S

c.1237C>T

1 paper

NM_006342.3

p.Q375*

c.1123C>T

1 paper

NM_006342.3

p.P417S

c.1249C>T

2 papers

NM_006342.3

p.P417L

c.1250C>T