Varaico: Literature-Extracted Genetic Variants

TACC3

199 papers

RefSeq Summary

This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This prot...

Pfam Domains

Aurora-A_bind_TACC3aa 522–563UCSCTACC3, Aurora-A binding region

TACC_Caa 639–832UCSCTransforming acidic coiled-coil-containing protein (TACC), C-terminal

Gene Aliases

HGNC Name

transforming acidic coiled-coil containing protein 3

HGNC Alias Symbols

ERIC1; ERIC-1; maskin; Tacc4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006342.3

p.G514R

c.1540G>C

Surrounding Variants

1 paper

NM_006342.3

p.G514R

c.1540G>A

6 papers

NM_006342.3

p.G514E

c.1541G>A

1 paper

NM_006342.3

p.A517A

c.1551C>T

1 paper

NM_006342.3

p.E519Q

c.1555G>C

1 paper

NM_006342.3

p.P499S

c.1495C>T

1 paper

NM_006342.3

p.K487E

c.1459A>G

1 paper

NM_006342.3

p.A484T

c.1450G>A

1 paper

NM_006342.3

p.V474L

c.1420G>T

1 paper

NM_006342.3

p.A469V

c.1406C>T

1 paper

NM_006342.3

p.A469T

c.1405G>A

1 paper

NM_006342.3

p.A469delins

c.1405_1406delinsTC

1 paper

NM_006342.3

p.Q463*

c.1387C>T