Varaico: Literature-Extracted Genetic Variants

TACC3

199 papers

RefSeq Summary

This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This prot...

Pfam Domains

Aurora-A_bind_TACC3aa 522–563UCSCTACC3, Aurora-A binding region

TACC_Caa 639–832UCSCTransforming acidic coiled-coil-containing protein (TACC), C-terminal

Gene Aliases

HGNC Name

transforming acidic coiled-coil containing protein 3

HGNC Alias Symbols

ERIC1; ERIC-1; maskin; Tacc4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006342.3

p.V577L

c.1729G>T

Surrounding Variants

1 paper

NM_006342.3

p.V577L

c.1729G>C

1 paper

NM_006342.3

p.R573K

c.1718G>A

1 paper

NM_006342.3

p.S582N

c.1745G>A

1 paper

NM_006342.3

p.L567R

c.1700T>G

5 papers

NM_006342.3

p.S558A

c.1672T>G

1 paper

NM_006342.3

p.S552A

c.1654T>G

1 paper

NM_006342.3

p.S547A

c.1639T>G

1 paper

NM_006342.3

p.T546_S547del2

c.1636_1640del6

4 papers

NM_006342.3

p.E542K

c.1624G>A

1 paper

NM_006342.3

p.D539E

c.1617T>A

1 paper

NM_006342.3

p.D539E

c.1617T>G

1 paper

NM_006342.3

p.T534S

c.1600A>T