TATA-box binding protein associated factor 12

TAF2J

TAFII20

TATA box binding protein (TBP)-associated factor, RNA polymerase II, J, 20kD

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

Transcription initiation factor TFIID subunit 12

Transcription initiation factor TFIID 20/15 kDa subunits

TAFII-20/TAFII-15

TAFII20/TAFII15

Transcription initiation factor TFIID subunit A

Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2008].

Varaico: Literature-Extracted Genetic Variants

TAF12

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol