Varaico: Literature-Extracted Genetic Variants

TAF1B

149 papers

RefSeq Summary

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. Th...

Pfam Domains

Zn_ribbon_RRN7aa 7–39UCSCZinc-finger of RNA-polymerase I-specific TFIIB, Rrn7

Rrn7_cyclin_Naa 162–254UCSCRrn7/TAF1B, N-terminal cyclin domain

Rrn7_cyclin_Caa 270–460UCSCRrn7/TAF1B, C-terminal cyclin domain

Gene Aliases

HGNC Name

TATA-box binding protein associated factor, RNA polymerase I subunit B

HGNC Alias Symbols

TAFI63; SL1; RAF1B; RAFI63

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005680.3

p.E430K

c.1288G>A

Surrounding Variants

1 paper

NM_005680.3

p.D439N

c.1315G>A

1 paper

NM_005680.3

p.D439E

c.1317C>A

1 paper

NM_005680.3

p.D439E

c.1317C>G

1 paper

NM_005680.3

p.R447delFs

c.1339delA

1 paper

NM_005680.3

p.R447fs

c.1339_1340fs

1 paper

NM_005680.3

p.T459K

c.1376C>A

5 papers

NM_005680.3

p.E462D

c.1386G>C

5 papers

NM_005680.3

p.E462D

c.1386G>T

1 paper

NM_005680.3

p.T464A

c.1390A>G

2 papers

NM_005680.3

p.K470delFs

c.1410delA

1 paper

NM_005680.3

p.K470fs

c.1408_1409fs

3 papers

NM_005680.3

p.T487M

c.1460C>T