Varaico: Literature-Extracted Genetic Variants

Gene:TAOK3
Variant:p.P219L

TAOK3

90 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine protein kinase that activates the p38/MAPK14 stress-activated MAPK cascade but inhibits the basal activity of the MAPK8/JNK cascade. The encoded ...

Pfam Domains

Pkinaseaa 24–277UCSCProtein kinase domain

Gene Aliases

HGNC Name

TAO kinase 3

HGNC Alias Symbols

JIK; DPK; MAP3K18

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_016281.4
p.P219L
c.656C>T
Surrounding Variants
1 paper
NM_016281.4
p.I233V
c.697A>G
1 paper
NM_016281.4
p.P262L
c.785C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."