Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007375.4

p.R6R

c.18G>C

Surrounding Variants

1 paper

NM_007375.4

p.R6G

c.16C>G

1 paper

NM_007375.4

p.R6W

c.16C>T

1 paper

NM_007375.4

p.V7G

c.20T>G

1 paper

NM_007375.4

p.V7V

c.21A>G

4 papers

NM_007375.4

p.T8A

c.22A>G

2 papers

NM_007375.4

p.I5T

c.14T>C

1 paper

NM_007375.4

p.T8I

c.23C>T

1 paper

NM_007375.4

p.T8T

c.24C>G

1 paper

NM_007375.4

p.T8T

c.24C>T

1 paper

NM_007375.4

p.Y4*

c.12T>A

1 paper

NM_007375.4

p.Y4F

c.11A>T

1 paper

NM_007375.4

p.E9Q

c.25G>C