Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_007375.4

p.D23A

c.68A>C

Surrounding Variants

1 paper

NM_007375.4

p.D23insFs

c.68_69insG

1 paper

NM_007375.4

p.D23N

c.67G>A

1 paper

NM_007375.4

p.D23E

c.69T>A

1 paper

NM_007375.4

p.D23E

c.69T>G

2 papers

NM_007375.4

p.D23_G24insFs

c.69_70insG

1 paper

NM_007375.4

p.G24delFs

c.70delG

4 papers

NM_007375.4

p.D22G

c.65A>G

4 papers

NM_007375.4

p.G24E

c.71G>A

2 papers

NM_007375.4

p.G24G

c.72G>C

1 paper

NM_007375.4

p.D22insFs

c.64_65insC

1 paper

NM_007375.4

p.D22fs

c.64_65fs

1 paper

NM_007375.4

p.G24G

c.72G>T