Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007375.4

p.F35Y

c.104T>A

Surrounding Variants

1 paper

NM_007375.4

p.F35I

c.103T>A

1 paper

NM_007375.4

p.Q34Q

c.102G>A

1 paper

NM_007375.4

p.Q34H

c.102G>C

1 paper

NM_007375.4

p.Q34_V47delFs

c.102_139del38

1 paper

NM_007375.4

p.P36R

c.107C>G

1 paper

NM_007375.4

p.Q34K

c.100C>A

1 paper

NM_007375.4

p.Q34fs

c.100_101fs

2 papers

NM_007375.4

p.Q34*

c.100C>T

1 paper

NM_007375.4

p.A33A

c.99C>T

19 papers

NM_007375.4

p.G37R

c.109G>A

19 papers

NM_007375.4

p.G37R

c.109G>C

2 papers

NM_007375.4

p.A33V

c.98C>T