Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007375.4

p.V96A

c.287T>C

Surrounding Variants

1 paper

NM_007375.4

p.V96V

c.288G>A

3 papers

NM_007375.4

p.K95R

c.284A>G

2 papers

NM_007375.4

p.K97R

c.290A>G

1 paper

NM_007375.4

p.R98*

c.292A>T

1 paper

NM_007375.4

p.R98R

c.294A>G

2 papers

NM_007375.4

p.V94M

c.280G>A

1 paper

NM_007375.4

p.A99T

c.295G>A

26 papers

NM_007375.4

p.A99P

c.295G>C

2 papers

NM_007375.4

p.A99S

c.295G>T

2 papers

NM_007375.4

p.A93V

c.278C>T

1 paper

NM_007375.4

p.A93P

c.277G>C

4 papers

NM_007375.4

p.V100I

c.298G>A