Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

94 papers

NM_007375.4

p.N267S

c.800A>G

Surrounding Variants

1 paper

NM_007375.4

p.N267I

c.800A>T

1 paper

NM_007375.4

p.N267D

c.799A>G

1 paper

NM_007375.4

p.R268G

c.802A>G

1 paper

NM_007375.4

p.Q269*

c.805C>T

1 paper

NM_007375.4

p.Q269L

c.806A>T

1 paper

NM_007375.4

p.K263R

c.788A>G

1 paper

NM_007375.4

p.K263Q

c.787A>C

86 papers

NM_007375.4

p.K263E

c.787A>G

5 papers

NM_007375.4

p.S273C

c.817A>T

2 papers

NM_007375.4

p.E261A

c.782A>C

1 paper

NM_007375.4

p.E261K

c.781G>A

1 paper

NM_007375.4

p.A260A

c.780C>T