Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007375.4

p.F283L

c.849T>A

Surrounding Variants

1 paper

NM_007375.4

p.F283L

c.849T>G

1 paper

NM_007375.4

p.G284R

c.850G>A

1 paper

NM_007375.4

p.G284R

c.850G>C

1 paper

NM_007375.4

p.G284W

c.850G>T

2 papers

NM_007375.4

p.F283Y

c.848T>A

1 paper

NM_007375.4

p.F283L

c.847T>C

1 paper

NM_007375.4

p.N285D

c.853A>G

1 paper

NM_007375.4

p.N285S

c.854A>G

2 papers

NM_007375.4

p.Q286*

c.856C>T

1 paper

NM_007375.4

p.G281V

c.842G>T

1 paper

NM_007375.4

p.G281R

c.841G>C

2 papers

NM_007375.4

p.G281C

c.841G>T