Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

45 papers

NM_007375.4

p.M311V

c.931A>G

Surrounding Variants

2 papers

NM_007375.4

p.G310R

c.928G>A

1 paper

NM_007375.4

p.G310R

c.928G>C

1 paper

NM_007375.4

p.N312S

c.935A>G

2 papers

NM_007375.4

p.F313L

c.937T>C

1 paper

NM_007375.4

p.F313Y

c.938T>A

2 papers

NM_007375.4

p.F313L

c.939T>A

2 papers

NM_007375.4

p.F313L

c.939T>G

1 paper

NM_007375.4

p.G308S

c.922G>A

1 paper

NM_007375.4

p.M307I

c.921G>A

2 papers

NM_007375.4

p.G314A

c.941G>C

5 papers

NM_007375.4

p.G314V

c.941G>T

700 papers

NM_007375.4

p.A315T

c.943G>A