Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_007375.4

p.A328T

c.982G>A

Surrounding Variants

5 papers

NM_007375.4

p.A328P

c.982G>C

3 papers

NM_007375.4

p.A328V

c.983C>T

1 paper

NM_007375.4

p.Q327L

c.980A>T

1 paper

NM_007375.4

p.A326T

c.976G>A

20 papers

NM_007375.4

p.A326P

c.976G>C

1 paper

NM_007375.4

p.A325A

c.975C>T

1 paper

NM_007375.4

p.L330R

c.989T>G

3 papers

NM_007375.4

p.L330L

c.990A>G

1 paper

NM_007375.4

p.A325V

c.974C>T

496 papers

NM_007375.4

p.Q331K

c.991C>A

1 paper

NM_007375.4

p.A325T

c.973G>A

1 paper

NM_007375.4

p.A324A

c.972T>A