Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_007375.4

p.G351A

c.1052G>C

Surrounding Variants

1 paper

NM_007375.4

p.N352D

c.1054A>G

19 papers

NM_007375.4

p.N352T

c.1055A>C

115 papers

NM_007375.4

p.N352S

c.1055A>G

2 papers

NM_007375.4

p.Q354E

c.1060C>G

1 paper

NM_007375.4

p.G348D

c.1043G>A

47 papers

NM_007375.4

p.G348V

c.1043G>T

11 papers

NM_007375.4

p.G348R

c.1042G>C

228 papers

NM_007375.4

p.G348C

c.1042G>T

1 paper

NM_007375.4

p.N355K

c.1065C>A

2 papers

NM_007375.4

p.N355K

c.1065C>G

94 papers

NM_007375.4

p.N345K

c.1035C>A

94 papers

NM_007375.4

p.N345K

c.1035C>G