Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

95 papers

NM_007375.4

p.R361S

c.1083G>T

Surrounding Variants

95 papers

NM_007375.4

p.R361S

c.1083G>C

22 papers

NM_007375.4

p.R361T

c.1082G>C

1 paper

NM_007375.4

p.R361Fs

c.1081delinsATTFs

1 paper

NM_007375.4

p.R361G

c.1081A>G

1 paper

NM_007375.4

p.E362G

c.1085A>G

1 paper

NM_007375.4

p.E362E

c.1086G>A

3 papers

NM_007375.4

p.E362D

c.1086G>C

1 paper

NM_007375.4

p.E362D

c.1086G>T

39 papers

NM_007375.4

p.P363A

c.1087C>G

1 paper

NM_007375.4

p.P363S

c.1087C>T

1 paper

NM_007375.4

p.Q360E

c.1078C>G

1 paper

NM_007375.4

p.Q360_R361Fs

c.1078_1081delinsATTFs