Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_007375.4

p.G376V

c.1127G>T

Surrounding Variants

62 papers

NM_007375.4

p.G376D

c.1127G>A

1 paper

NM_007375.4

p.G376A

c.1127G>C

1 paper

NM_007375.4

p.G376G

c.1128C>T

3 papers

NM_007375.4

p.S377T

c.1129T>A

1 paper

NM_007375.4

p.S377insFs

c.1131dupT

26 papers

NM_007375.4

p.S375G

c.1123A>G

1 paper

NM_007375.4

p.N378_I383del0

c.1133_1147del15

51 papers

NM_007375.4

p.N378D

c.1132A>G

78 papers

NM_007375.4

p.Y374*

c.1122T>A

1 paper

NM_007375.4

p.Y374Y

c.1122T>C

79 papers

NM_007375.4

p.Y374*

c.1122T>G

23 papers

NM_007375.4

p.N378S

c.1133A>G