Varaico: Literature-Extracted Genetic Variants

TARDBP

2,553 papers

RefSeq Summary

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expr...

Pfam Domains

TDP-43_Naa 4–77UCSCTAR DNA-binding protein 43, N-terminal domain

RRM_1aa 106–172UCSCRNA recognition motif

RRM_1aa 193–243UCSCRNA recognition motif

TDP-43_Caa 262–372UCSCTAR DNA-binding protein 43, C-terminal

Gene Aliases

HGNC Name

TAR DNA binding protein

HGNC Alias Symbols

TDP-43; ALS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007375.4

p.F401L

c.1201T>C

Surrounding Variants

1 paper

NM_007375.4

p.F401Y

c.1202T>A

1 paper

NM_007375.4

p.F401L

c.1203T>A

1 paper

NM_007375.4

p.F401L

c.1203T>G

3 papers

NM_007375.4

p.S403A

c.1207T>G

1 paper

NM_007375.4

p.S403*

c.1208C>A

1 paper

NM_007375.4

p.S403*

c.1208C>G

1 paper

NM_007375.4

p.F397L

c.1191T>A

1 paper

NM_007375.4

p.F397L

c.1191T>G

1 paper

NM_007375.4

p.F397Y

c.1190T>A

1 paper

NM_007375.4

p.M405L

c.1213A>C

3 papers

NM_007375.4

p.M405V

c.1213A>G

1 paper

NM_007375.4

p.M405L

c.1213A>T