Varaico: Literature-Extracted Genetic Variants

TARS1

61 papers

RefSeq Summary

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-...

Pfam Domains

TGSaa 83–143UCSCTGS domain

tRNA_SADaa 249–298UCSCThreonyl and Alanyl tRNA synthetase second additional domain

tRNA-synt_2baa 397–608UCSCtRNA synthetase class II core domain (G, H, P, S and T)

HGTP_anticodonaa 620–711UCSCAnticodon binding domain

Gene Aliases

HGNC Name

threonyl-tRNA synthetase 1

HGNC Previous Name

threonyl-tRNA synthetase

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_152295.5

p.F2Y

c.5T>A

Surrounding Variants

1 paper

NM_152295.5

p.F2L

c.6T>A

1 paper

NM_152295.5

p.F2L

c.4T>C

1 paper

NM_152295.5

p.F2L

c.6T>G

1 paper

NM_152295.5

p.M1V

c.1A>G

1 paper

NM_152295.5

p.K5R

c.14A>G

1 paper

NM_152295.5

p.P9fs

c.25_26fs

1 paper

NM_152295.5

p.G30A

c.89G>C

1 paper

NM_152295.5

p.Y53F

c.158A>T

1 paper

NM_152295.5

p.Y55F

c.164A>T

1 paper

NM_152295.5

p.M60K

c.179T>A

1 paper

NM_152295.5

p.I63V

c.187A>G

1 paper

NM_152295.5

p.I63M

c.189A>G