Varaico: Literature-Extracted Genetic Variants

TAS1R1

152 papers

RefSeq Summary

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-en...

Pfam Domains

ANF_receptoraa 74–457UCSCReceptor family ligand binding region

NCD3Gaa 492–545UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 560–811UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

taste 1 receptor member 1

HGNC Previous Symbol

GPR70

Papers

RefSeq ID

Protein change

DNA change

1–12 of 184 variants

10 papers

NM_138697.4

p.A372T

c.1114G>A

8 papers

NM_138697.4

p.K347E

c.1039A>G

6 papers

NM_138697.4

p.A110V

c.329C>T

6 papers

NM_138697.4

p.Q124H

c.372A>T

4 papers

NM_138697.4

p.S356C

c.1067C>G

4 papers

NM_138697.4

p.R507Q

c.1520G>A

4 papers

NM_138697.4

p.R652H

c.1955G>A

3 papers

NM_138697.4

p.Q181E

c.541C>G

3 papers

NM_138697.4

p.T575_L576del1

c.1725_1727delGCT

3 papers

NM_138697.4

p.R603C

c.1807C>T

3 papers

NM_138697.4

p.R603H

c.1808G>A

2 papers

NM_138697.4

p.Y100F

c.299A>T