Varaico: Literature-Extracted Genetic Variants

TAS1R1

152 papers

RefSeq Summary

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-en...

Pfam Domains

ANF_receptoraa 74–457UCSCReceptor family ligand binding region

NCD3Gaa 492–545UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 560–811UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

taste 1 receptor member 1

HGNC Previous Symbol

GPR70

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_138697.4

p.Y100F

c.299A>T

Surrounding Variants

1 paper

NM_138697.4

p.Q101L

c.302A>T

1 paper

NM_138697.4

p.Y103F

c.308A>T

1 paper

NM_138697.4

p.N95S

c.284A>G

2 papers

NM_138697.4

p.S107_D108delFs

c.321_322delTG

6 papers

NM_138697.4

p.A110V

c.329C>T

1 paper

NM_138697.4

p.T90M

c.269C>T

1 paper

NM_138697.4

p.V112E

c.335T>A

2 papers

NM_138697.4

p.T115M

c.344C>T

1 paper

NM_138697.4

p.T115T

c.345G>A

1 paper

NM_138697.4

p.V118M

c.352G>A

1 paper

NM_138697.4

p.R80W

c.238C>T

1 paper

NM_138697.4

p.M79delFs

c.235delA