Varaico: Literature-Extracted Genetic Variants

TAS1R1

152 papers

RefSeq Summary

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-en...

Pfam Domains

ANF_receptoraa 74–457UCSCReceptor family ligand binding region

NCD3Gaa 492–545UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 560–811UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

taste 1 receptor member 1

HGNC Previous Symbol

GPR70

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_138697.4

p.I167I

c.501T>C

Surrounding Variants

1 paper

NM_138697.4

p.S168G

c.502A>G

1 paper

NM_138697.4

p.A170E

c.509C>A

1 paper

NM_138697.4

p.T175A

c.523A>G

1 paper

NM_138697.4

p.R180W

c.538C>T

1 paper

NM_138697.4

p.R180Q

c.539G>A

3 papers

NM_138697.4

p.Q181E

c.541C>G

1 paper

NM_138697.4

p.R187C

c.559C>T

1 paper

NM_138697.4

p.I189T

c.566T>C

1 paper

NM_138697.4

p.P190A

c.568C>G

1 paper

NM_138697.4

p.N191D

c.571A>G

2 papers

NM_138697.4

p.N191S

c.572A>G

2 papers

NM_138697.4

p.D192delFs

c.575_576delAC