Varaico: Literature-Extracted Genetic Variants

TAS1R1

152 papers

RefSeq Summary

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-en...

Pfam Domains

ANF_receptoraa 74–457UCSCReceptor family ligand binding region

NCD3Gaa 492–545UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 560–811UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

taste 1 receptor member 1

HGNC Previous Symbol

GPR70

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_138697.4

p.S217C

c.649A>T

Surrounding Variants

1 paper

NM_138697.4

p.L223L

c.667C>T

1 paper

NM_138697.4

p.W210*

c.630G>A

2 papers

NM_138697.4

p.Q226E

c.676C>G

1 paper

NM_138697.4

p.K205Q

c.613A>C

1 paper

NM_138697.4

p.T233A

c.697A>G

1 paper

NM_138697.4

p.L201V

c.601C>G

1 paper

NM_138697.4

p.Q235del1

c.703_704delCAG

1 paper

NM_138697.4

p.Q235delFs

c.704_705delAG

2 papers

NM_138697.4

p.I237L

c.709A>C

1 paper

NM_138697.4

p.I237F

c.709A>T

1 paper

NM_138697.4

p.D192E

c.576C>A

1 paper

NM_138697.4

p.D192E

c.576C>G