Varaico: Literature-Extracted Genetic Variants

TAS1R1

152 papers

RefSeq Summary

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-en...

Pfam Domains

ANF_receptoraa 74–457UCSCReceptor family ligand binding region

NCD3Gaa 492–545UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 560–811UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

taste 1 receptor member 1

HGNC Previous Symbol

GPR70

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_138697.4

p.V324M

c.970G>A

Surrounding Variants

1 paper

NM_138697.4

p.Q327*

c.979C>T

2 papers

NM_138697.4

p.V321_L322del1

c.963_965delGCT

2 papers

NM_138697.4

p.V321_L322del2

c.961_965del6

1 paper

NM_138697.4

p.S306A

c.916T>G

1 paper

NM_138697.4

p.W303*

c.909G>A

1 paper

NM_138697.4

p.A302D

c.905C>A

1 paper

NM_138697.4

p.K346fs

c.1036_1037fs

1 paper

NM_138697.4

p.A302T

c.904G>A

1 paper

NM_138697.4

p.K346insFs

c.1038dupG

1 paper

NM_138697.4

p.E301A

c.902A>C

8 papers

NM_138697.4

p.K347E

c.1039A>G

2 papers

NM_138697.4

p.A299T

c.895G>A