Varaico: Literature-Extracted Genetic Variants

TAS1R1

152 papers

RefSeq Summary

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-en...

Pfam Domains

ANF_receptoraa 74–457UCSCReceptor family ligand binding region

NCD3Gaa 492–545UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 560–811UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

taste 1 receptor member 1

HGNC Previous Symbol

GPR70

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_138697.4

p.R507Q

c.1520G>A

Surrounding Variants

2 papers

NM_138697.4

p.R507G

c.1519C>G

1 paper

NM_138697.4

p.V508fs

c.1522_1523fs

1 paper

NM_138697.4

p.V508_V509delFs

c.1524_1525delGG

2 papers

NM_138697.4

p.T510M

c.1529C>T

1 paper

NM_138697.4

p.E503K

c.1507G>A

1 paper

NM_138697.4

p.K530*

c.1588A>T

1 paper

NM_138697.4

p.I483T

c.1448T>C

1 paper

NM_138697.4

p.T470A

c.1408A>G

1 paper

NM_138697.4

p.V465I

c.1393G>A

1 paper

NM_138697.4

p.T464T

c.1392G>A

1 paper

NM_138697.4

p.N442_R443delFs

c.1326_1327delCA

1 paper

NM_138697.4

p.Q420_L421Splc

c.1261-90C>T