Varaico: Literature-Extracted Genetic Variants

TAS1R1

152 papers

RefSeq Summary

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-en...

Pfam Domains

ANF_receptoraa 74–457UCSCReceptor family ligand binding region

NCD3Gaa 492–545UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 560–811UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

taste 1 receptor member 1

HGNC Previous Symbol

GPR70

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_138697.4

p.R603H

c.1808G>A

Surrounding Variants

3 papers

NM_138697.4

p.R603C

c.1807C>T

1 paper

NM_138697.4

p.F622fs

c.1864_1865fs

1 paper

NM_138697.4

p.P626L

c.1877C>T

1 paper

NM_138697.4

p.L579V

c.1735C>G

3 papers

NM_138697.4

p.T575_L576del1

c.1725_1727delGCT

2 papers

NM_138697.4

p.T575_L576del2

c.1723_1727del6

2 papers

NM_138697.4

p.R634H

c.1901G>A

1 paper

NM_138697.4

p.L570_L571del0

c.1708_1713del6

2 papers

NM_138697.4

p.H565N

c.1693C>A

1 paper

NM_138697.4

p.L560fs

c.1678_1679fs

1 paper

NM_138697.4

p.L560insFs

c.1679dupT

1 paper

NM_138697.4

p.R652C

c.1954C>T