Varaico: Literature-Extracted Genetic Variants

TAS1R1

152 papers

RefSeq Summary

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-en...

Pfam Domains

ANF_receptoraa 74–457UCSCReceptor family ligand binding region

NCD3Gaa 492–545UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 560–811UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

taste 1 receptor member 1

HGNC Previous Symbol

GPR70

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_138697.4

p.V683delFs

c.2048_2049delTG

Surrounding Variants

1 paper

NM_138697.4

p.G678R

c.2032G>C

2 papers

NM_138697.4

p.A689V

c.2066C>T

1 paper

NM_138697.4

p.Q690fs

c.2068_2069fs

2 papers

NM_138697.4

p.Q690delFs

c.2070delG

1 paper

NM_138697.4

p.L698Q

c.2093T>A

1 paper

NM_138697.4

p.P703S

c.2107C>T

1 paper

NM_138697.4

p.L704_P705del2

c.2110_2114del6

1 paper

NM_138697.4

p.I659I

c.1977C>T

1 paper

NM_138697.4

p.A706V

c.2117C>T

4 papers

NM_138697.4

p.R652H

c.1955G>A

1 paper

NM_138697.4

p.R652C

c.1954C>T

2 papers

NM_138697.4

p.R634H

c.1901G>A