Varaico: Literature-Extracted Genetic Variants

TAS1R1

152 papers

RefSeq Summary

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-en...

Pfam Domains

ANF_receptoraa 74–457UCSCReceptor family ligand binding region

NCD3Gaa 492–545UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 560–811UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

taste 1 receptor member 1

HGNC Previous Symbol

GPR70

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_138697.4

p.P810R

c.2429C>G

Surrounding Variants

1 paper

NM_138697.4

p.G803S

c.2407G>A

1 paper

NM_138697.4

p.R818C

c.2452C>T

1 paper

NM_138697.4

p.P819T

c.2455C>A

1 paper

NM_138697.4

p.S801C

c.2401A>T

1 paper

NM_138697.4

p.I831fs

c.2491_2492fs

1 paper

NM_138697.4

p.G839G

c.2517C>T

1 paper

NM_138697.4

p.S772C

c.2315C>G

1 paper

NM_138697.4

p.V771M

c.2311G>A

1 paper

NM_138697.4

p.V762_T763delFs

c.2286_2287delCA

1 paper

NM_138697.4

p.V762fs

c.2284_2285fs

1 paper

NM_138697.4

p.N755K

c.2265C>A

1 paper

NM_138697.4

p.N755K

c.2265C>G