Varaico: Literature-Extracted Genetic Variants

TBK1

739 papers

RefSeq Summary

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB...

Pfam Domains

Pkinaseaa 9–299UCSCProtein kinase domain

TBK1_ULDaa 308–395UCSCTANK binding kinase 1 ubiquitin-like domain

TBK1_CCD1aa 400–655UCSCTANK-binding kinase 1 coiled-coil domain 1

Gene Aliases

HGNC Name

TANK binding kinase 1

HGNC Alias Symbol

NAK

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_013254.4

p.K38R

c.113A>G

Surrounding Variants

1 paper

NM_013254.4

p.I37I

c.111C>A

2 papers

NM_013254.4

p.I37T

c.110T>C

1 paper

NM_013254.4

p.I37insFs

c.110_111insC

1 paper

NM_013254.4

p.I37L

c.109A>C

1 paper

NM_013254.4

p.F40I

c.118T>A

1 paper

NM_013254.4

p.A36P

c.106G>C

2 papers

NM_013254.4

p.F35F

c.105T>C

1 paper

NM_013254.4

p.N41S

c.122A>G

1 paper

NM_013254.4

p.N42H

c.124A>C

4 papers

NM_013254.4

p.N42S

c.125A>G

5 papers

NM_013254.4

p.I43V

c.127A>G

1 paper

NM_013254.4

p.D33A

c.98A>C