Varaico: Literature-Extracted Genetic Variants

TBK1

739 papers

RefSeq Summary

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB...

Pfam Domains

Pkinaseaa 9–299UCSCProtein kinase domain

TBK1_ULDaa 308–395UCSCTANK binding kinase 1 ubiquitin-like domain

TBK1_CCD1aa 400–655UCSCTANK-binding kinase 1 coiled-coil domain 1

Gene Aliases

HGNC Name

TANK binding kinase 1

HGNC Alias Symbol

NAK

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_013254.4

p.G159D

c.476G>A

Surrounding Variants

14 papers

NM_013254.4

p.G159A

c.476G>C

1 paper

NM_013254.4

p.G159G

c.477T>A

1 paper

NM_013254.4

p.F158C

c.473T>G

1 paper

NM_013254.4

p.D157E

c.471T>A

1 paper

NM_013254.4

p.D157E

c.471T>G

1 paper

NM_013254.4

p.T156_D157delFs

c.468_469delAG

1 paper

NM_013254.4

p.T156fs

c.466_467fs

5 papers

NM_013254.4

p.T156fs

c.466_467fs

1 paper

NM_013254.4

p.T156insFs

c.466dupA

1 paper

NM_013254.4

p.L155H

c.464T>A

7 papers

NM_013254.4

p.T156delFs

c.467_468delCA

1 paper

NM_013254.4

p.K154N

c.462A>C