Varaico: Literature-Extracted Genetic Variants

TCF7

210 papers

RefSeq Summary

This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and...

Pfam Domains

CTNNB1_bindingaa 10–212UCSCN-terminal CTNNB1 binding

HMG_boxaa 269–337UCSCHMG (high mobility group) box

Gene Aliases

HGNC Name

transcription factor 7

HGNC Alias Symbol

TCF-1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 108 variants

2 papers

NM_003202.5

p.P20L

c.59C>T

2 papers

NM_003202.5

p.Q92H

c.276G>T

2 papers

NM_003202.5

p.L107R

c.320T>G

2 papers

NM_003202.5

p.P154delFs

c.460delC

2 papers

NM_003202.5

p.H155N

c.463C>A

2 papers

NM_003202.5

p.H155fs

c.463_464fs

2 papers

NM_003202.5

p.L198M

c.592C>A

2 papers

NM_003202.5

p.A256T

c.766G>A

2 papers

NM_003202.5

p.L273L

c.819C>T

2 papers

NM_003202.5

p.W336C

c.1008G>C

2 papers

NM_003202.5

p.W336C

c.1008G>T

2 papers

NM_003202.5

p.V383L

c.1147G>C