Varaico: Literature-Extracted Genetic Variants

TCF7

210 papers

RefSeq Summary

This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and...

Pfam Domains

CTNNB1_bindingaa 10–212UCSCN-terminal CTNNB1 binding

HMG_boxaa 269–337UCSCHMG (high mobility group) box

Gene Aliases

HGNC Name

transcription factor 7

HGNC Alias Symbol

TCF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003202.5

p.P96P

c.288G>C

Surrounding Variants

2 papers

NM_003202.5

p.Q92H

c.276G>T

1 paper

NM_003202.5

p.A91insFs

c.271dupG

1 paper

NM_003202.5

p.E81*

c.241G>T

1 paper

NM_003202.5

p.G73G

c.219G>T

1 paper

NM_003202.5

p.G106Splc

c.316+223C>T

1 paper

NM_003202.5

p.G61S

c.181G>A

1 paper

NM_003202.5

p.S59F

c.176C>T

1 paper

NM_003202.5

p.S59fs

c.175_176fs

1 paper

NM_003202.5

p.E58D

c.174G>C

1 paper

NM_003202.5

p.E58_E60delFs

c.174_178del5

1 paper

NM_003202.5

p.L51insFs

c.151_152insTG

1 paper

NM_003202.5

p.D47N

c.139G>A