Varaico: Literature-Extracted Genetic Variants

TCF7

210 papers

RefSeq Summary

This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and...

Pfam Domains

CTNNB1_bindingaa 10–212UCSCN-terminal CTNNB1 binding

HMG_boxaa 269–337UCSCHMG (high mobility group) box

Gene Aliases

HGNC Name

transcription factor 7

HGNC Alias Symbol

TCF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003202.5

p.S135S

c.405G>C

Surrounding Variants

1 paper

NM_003202.5

p.S135L

c.404C>T

1 paper

NM_003202.5

p.G136R

c.406G>A

1 paper

NM_003202.5

p.G136R

c.406G>C

1 paper

NM_003202.5

p.P134T

c.400C>A

1 paper

NM_003202.5

p.P132delFs

c.395delC

1 paper

NM_003202.5

p.H140Q

c.420C>G

1 paper

NM_003202.5

p.P143P

c.429G>T

1 paper

NM_003202.5

p.Y122C

c.365A>G

1 paper

NM_003202.5

p.V121I

c.361G>A

1 paper

NM_003202.5

p.G115S

c.343G>A

1 paper

NM_003202.5

p.C112R

c.334T>C

1 paper

NM_003202.5

p.K108E

c.322A>G