Varaico: Literature-Extracted Genetic Variants

TCF7

210 papers

RefSeq Summary

This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and...

Pfam Domains

CTNNB1_bindingaa 10–212UCSCN-terminal CTNNB1 binding

HMG_boxaa 269–337UCSCHMG (high mobility group) box

Gene Aliases

HGNC Name

transcription factor 7

HGNC Alias Symbol

TCF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003202.5

p.Y163D

c.487T>G

Surrounding Variants

1 paper

NM_003202.5

p.L162V

c.484C>G

1 paper

NM_003202.5

p.N167I

c.500A>T

1 paper

NM_003202.5

p.H155_G156insFs

c.465_466insC

2 papers

NM_003202.5

p.H155N

c.463C>A

2 papers

NM_003202.5

p.H155fs

c.463_464fs

1 paper

NM_003202.5

p.P171S

c.511C>T

1 paper

NM_003202.5

p.P153L

c.458C>T

1 paper

NM_003202.5

p.H155insFs

c.463dupC

2 papers

NM_003202.5

p.P154delFs

c.460delC

1 paper

NM_003202.5

p.A174_I178del5

c.520_533del15

1 paper

NM_213648.5

p.N36N

c.108T>C

1 paper

NM_003202.5

p.N151_Q152insTG

c.451_455ins6